[SBIR/STTR Study Section Rosters]
The Renal and Urological Sciences Small Business Activities Special Emphasis Panel [RUS (10)] will review SBIR and STTR grant applications that focus primarily on kidney, urinary tract, and male genital system therapies, devices, and diagnostics. This includes clinical, translational and fundamental studies and investigators may employ a range of approaches that include genetics, genomics and proteomics, molecular, cell, and computational biology, biochemistry, biophysics and bioengineering, imaging, analyses of model organisms, and human studies.
Specific areas covered by the RUS Small Business SEP [RUS (10)]:
- Development and evaluation of new techniques for investigating, diagnosing and treating disorders of the kidney, urinary tract, and male genital system;
- Development of new techniques and evaluation of the efficacy of dialysis;
- Application of new technologies and methodologies to the diagnosis and treatment of urologic diseases;
- Novel approaches to regeneration and tissue engineering of the kidney, urinary tract and male genital system; and,
- Clinical assessment of genitourinary diseases including urinary incontinence and pelvic floor dysfunction.
The RUS Small Business SEP [RUS (10)] has the following shared interests outside the RUS IRG:
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With the Biological Chemistry and Macromolecular Biophysics [BCMB] IRG: Studies examining the structure and function of membranes or proteins involved in kidney physiology or pathophysiology could be assigned to the RUS Small Business SEP. Studies examining the general principles of membrane or protein structure and function that use renal tissue as a convenient source of material could be assigned to the BCMB IRG.
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With the Biology of Development and Aging [BDA] IRG: Applications studying the use of stem cell technology for renal or genitourinary tract specific issues could be assigned to the RUS Small Business SEP. BDA may be considered for more general developmental studies. Applications that use human embryonic stem cells might also be clustered in the BDA IRG, even if studying renal or urological system specific issues.
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With the Risk, Prevention, and Health Behavior [RPHB] and the Health of the Population [HOP] IRGs: Studies of behavior modification, including patient health education or training, directed toward the prevention and treatment of renal and urological system diseases, including psychological aspects, could be assigned to the RPHB IRG, or to the HOP IRG, depending on the level of analysis and the nature of the intervention. Applications on the diseases, disorders, or functional consequences of behaviors could be assigned to the RUS Small Business SEP. Health education or training directed to the health care provider, not the patient, should also be assigned to the RUS Small Business SEP.
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With the Oncological Sciences [ONC] IRG: Studies of diagnosis, prevention, treatment, and epidemiology of renal or urological cancers, including prostate cancer, would be assigned to the ONC IRG or to the HOP IRG, depending on the level of analysis. Applications focusing upon large numbers of persons or aggregates of persons would be assigned to the HOP IRG. Applications focusing on dysplasia and hyperplasia should be considered by the RUS Small Business SEP or to the HOP IRG, depending upon the level of analysis and the number of persons studied.
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With the Surgical Sciences, Biomedical Imaging, and Bioengineering [SBIB] IRG: (1) The SBIB IRG would be an appropriate assignment of applications focused on surgical aspects of transplantation and issues involving recovery of organs for transplantation and organ preservation. Applications that primarily address the implications of transplantation on kidney function could be reviewed in the RUS Small Business SEP. (2) Studies of biomarkers derived from the kidney to inform understanding and diagnosis/treatment of kidney diseases could be assigned to the RUS Small Business SEP. Studies of markers of function, such as might be developed for the radiological diagnosis of distribution of renal blood flow or epithelial cell function, could be assigned to the SBIB IRG. (3) Cell-cell interactions that determine functional alterations resulting from both acute and chronic events in the kidney could be assigned to the RUS Small Business SEP. Studies primarily dealing with surgical outcomes or with applied radiologic imaging could be assigned to the SBIB IRG. (4) Applications can be referred to the RUS Small Business SEP when the emphasis is on using imaging systems to obtain structural or functional information, or used in diagnosis or therapy, of the genitourinary track. When the emphasis of an application is on the design, development or validation of medical imaging systems, their components, or software, assignment could be to the SBIB IRG. (5) Studies involving tissue engineering could be referred to the RUS Small Business SEP when focused on specific applications to the genitourinary track. When the emphasis is on the integration of physical, chemical, mathematical or engineering principles in the design and development of engineered constructs assignment could be to the SBIB IRG.
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